Saturday, October 27, 2012

Macrophage

Macrophages


 function in both non-specific defense (innate immunity) as well as help initiate specific defense mechanisms (adaptive immunity) of vertebrate animals. Their role is to phagocytose, or engulf and then digest, cellular debris and pathogens, either as stationary or as mobile cells. They also stimulate lymphocytes and other immune cells to respond to pathogens. They are specialized phagocytic cells that attack foreign substances, infectious microbes and cancer cells through destruction and ingestion. Macrophages can be identified by specific expression of a number of proteins including

Name of cell Location

Dust cells =Alveolar macrophages pulmonary alveolus= of lungs
Histiocytes=  connective tissue
Kupffer cells = liver
Microglia = neural tissue
Epithelioid= cells granulomas
Osteoclasts =bone
Sinusoidal lining cells= spleen
Giant cells= Connective Tissue
Peritoneal macrophages= Peritoneal cavity



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