Showing posts with label vitamin D. Show all posts
Showing posts with label vitamin D. Show all posts

Tuesday, February 5, 2013

Vitamin D,eyes

Vitamin D dramatically improves eyesight of elderly



 Vitamin D deficiency is prevalent in many Western nations today, and is responsible for causing an epidemic of illness that touches nearly every aspect of human health. Even proper eyesight is contingent on adequate vitamin D intake, it turns out, as illustrated by a recent study that found a definitive link between increased vitamin D intake and improved eyesight in the elderly.



Researchers from University College London (UCL) in the U.K. made this discovery recently after reviewing earlier literature on the benefits of vitamin D in reducing and even eliminating the amyloid plaques in the brain associated with Alzheimer's disease. They hypothesized that perhaps vitamin D may also eliminate the toxic molecules responsible for causing macular degeneration.



In tests, this hypothesis was confirmed when the researchers administered nominal doses of vitamin D to one-year-old female mice. After being injected every three days with a solution containing safflower oil and about 0.9 micrograms (mcg), or roughly 40 international units (IU), of vitamin D for six weeks, or the equivalent of about 5.75 human years, the mice experienced considerable improvement.



Follow-up tests conducted at the conclusion of the six-week period found that mice given the vitamin solution, as opposed to an oil-only placebo, had a reduced number of inflammation-causing macrophages in their system. Deposits of amyloid beta, a degenerative toxin that can degrade eyesight, were also decreased as a result of the vitamin D.



Since amyloid beta is also associated with both Alzheimer's and heart disease, the overall benefits from increased vitamin D intake can also help prevent numerous other illnesses, even in doses far lower than what would be considered therapeutic. Supplementing daily with therapeutic doses of vitamin D, in other words, is "a very simple and effective route to limit disease progression," wrote the authors in their study, which was published in the journal Neurobiology and Aging.



"This research shows how close study of one part of the body can lead scientists to discover new knowledge that is more widely applicable," explained Prof. Douglas Kell, Chief Executive of the Biotechnology and Biological Sciences Research Council(BBSRC), which helped fund the study. "By studying the fundamental biology of one organ scientists can begin to draw links between a number of diseases in the hope of developing preventive strategies."



A study published in the journal Archives of Ophthalmology back in 2011 made similar observations, having found that people with high levels of vitamin D in their blood were far less likely to suffer age-related macular degeneration. Researchers noted that higher vitamin D levels were associated with about a 60 percent reduced risk of vision loss.

Tuesday, November 27, 2012

Vitamin D

Vitamin D - The Allopathic View 

 Vitamin D - The Allopathic View
This diagram shows the influence of sunlight, affecting the skin to synthesize some precursor vitamin D, passing through your blood, down to the liver, to be stored there. I said earlier that the liver is a great storing location.

It also shows on the right side that you can acquire some vitamin D through your diet, assimilate it in your blood through digestion and going to the same place, the liver. You can assimilate a little bit that way with few foods. By the way there is even a little bit in BioSuperfood. But really, there's more in fish, and so forth. I wouldn't recommend milk.

But besides the liver, it also shows here the kidney's participation in synthesizing, or supercharging vitamin D, the final factor, which at this stage is really a hormone created by specialized cells of the kidney. You can also see here on the right the stimulation from the para-thyroid gland. Earlier, I said that the parathyroid gland releases hormones, and that specialized cells of the kidney will receive these messages and synthesize vitamin D hormones. You can see here the process where cells of the kidney and cells of the liver work in tandem to charge vitamin D123 (a hormone).

Vitamin D supplementation exploded on the market in the last couple of years, when, three or four years ago, nobody talked about it. It hadn't been spotted yet as a deficiency in certain types of cancer. But with those recent observations and premature deductions, the vitamin D industry was born. That's similar to what happened to vitamin E starting in 1980. Due to some premature recommendations, it became a star supplement.

Now the fact that the vitamin D factors are important in intestinal absorption, in calcium and bone metabolism and prevention of cancer is real and we must be concerned with that. But there are many other components in our body that become deficient with loss of life force. And we have an opportunity to resolve these deficiencies in a very different way then supplementing. We want to restore the declining metabolism that leads to deficiencies.

Vitamin D - The Holistic View


Now, continuing on with vitamin D, in chart thirteen, you'll see that I've drawn lines. I've shown the brain's involvement from the HPA that supervises the pituitary, which controls the para-thyroid, which controls the kidney.
 Vitamin D - The Holistic View
Here we can see that the parathyroid glands would do nothing unless the HPA says "go ahead, please, we need some vitamin D." And know that with aging, fatigue, malnutrition, inflammation, etc., even the brain's requests for vitamin D slows down, and we have vitamin D deficiency.

With this visual, I hope you understand the importance of the HPA's relationship with our metabolism. Without the brain's action in restoring cellular energy, even if you go in the sun you're not going to get your proper vitamin D level restored. Even consuming food with vitamin D, and large amounts of vitamin D supplements will not be good.

All the aspects related to vitamin D activity, from reception of the sunlight, assimilation of your vitamins, its storage at the liver, its subsequent synthesis at the kidneys, all the way into the biochemistry of each cell and its Krebs cycle function will not work well, or at all without that HPA relationship.

The last thing I wanted to do with this chart was to show vitamin D as a separate event. You could not have the vitamin D metabolism working unless you also had acquisition of nutrients and transfer of energy, vitamin c, fat metabolism, mineral activity, and so on also working. In summary, all human metabolisms are inter-related. I'm trying to show the big picture.

Monday, November 19, 2012

Treasure your Bones ! Prevent Bone Loss

Specially Fermented Vegetables and Fennel are More Effective Than Calcium to Prevent Bone Loss

In most people, sometime during yours 30's your bone mass will start to gradually decline there are steps you can take to slow, or stop, this from occurring, which I'll discuss below.

For women, that bone loss speeds up significantly during the first 10 years after menopause, which is the period when osteoporosis often develops.

Many are under the mistaken impression that a prescription drug combined with megadose calcium supplements is the answer to strong and healthy bones.

In reality, as new research has once again revealed, nature has provided some of the best substances for preventing bone loss right in the foods you eat. Fermented vegetables using special starter culture designed to optimize vitamin K2 is one of your best strategies for maintaining healthy bones and preventing bone loss, in combination with vitamin D.

But before I get to that, recent research also suggests that one often-overlooked vegetable in particular can be of benefit, and if you've never had fennel, now might be a good time to give it a try.
Fennel May Prevent Post-Menopausal Bone Loss and Osteoporosis


Scientists looking for natural compounds to counteract postmenopausal bone loss believe they may have found the answer in fennel, a much under-appreciated vegetable that is native to southern Europe and the Mediterranean area.

In a study published in the International Journal of Molecular Medicine, it was found that eating the seeds of the plant had a beneficial effect on loss of bone mineral density, as well as bone mineral content.

Healthy bones maintain their strength through a continual process of bone breakdown and bone rebuilding. Osteoclasts are the cells that break down weakened bone, and osteoblasts are the cells that build it back up. The fennel appeared to work by reducing osteoclast differentiation and function, thereby slightly decreasing bone turnover markers and offering a protective effect on the bones.

Researchers indicated that fennel seeds show potential in preventing bone loss in postmenopausal osteoporosis. This vegetable, which has a celery-like base topped with feathery green leaves, has a long history of medicinal use, and has been valued since ancient times as a breath freshener, digestive aid, and for helping expel phlegm from the lungs.

It's now known that the plant is a treasure trove of nutrients, including vitamin C, folate (the natural form of folic acid), calcium, magnesium, and more, as well as phytonutrients and antioxidants that may help reduce inflammation, boost immune function, and even help prevent cancer.
Eating Plenty of Vegetables is Key for Bone Health


Fennel is just one example of a veggie that's excellent for your bones. High vegetable intake has been associated with positive effects on bone mineral status for years. Eating high quality, organic, biodynamic, locally grown veggies will naturally increase your bone density and strength, and will decrease your risk of developing a fracture at virtually any age.

One reason why this is so important is because it supplies your body with nutrients that are essential for bone health, like vitamin K1 and potassium.

Your body needs potassium to maintain proper pH levels in your body fluids, and optimize your sodium to potassium ratio which also affects your bone mass. If you eat a diet loaded with processed foods, there's a good chance your potassium to sodium ratio is far from optimal, which is typically done by consuming a diet of processed foods, which are notoriously low in potassium while high in sodium.

An imbalanced sodium to potassium ratio can contribute to a number of diseases, including osteoporosis. To ensure you get these two important nutrients in more appropriate ratios, simply ditch processed foods, which are very high in processed salt and low in potassium and other essential nutrients

Also eat a diet of whole, unprocessed foods, ideally organically grown to ensure optimal nutrient content. This type of diet will naturally provide much larger amounts of potassium in relation to sodium, which is optimal for your bone health, and your overall health. If you find it difficult to eat the recommended amount of vegetables you need daily, give vegetable juicing a try.
Vitamin K2 is Critical for Bone Health
Vitamin K2, also called menaquinone, is made by the bacteria that line your gastrointestinal tract. The biological role of vitamin K2 is to help move calcium into the proper areas in your body, such as your bones and teeth. It also plays a role in removing calcium from areas where it shouldn't be, such as in your arteries and soft tissues. It's critical for keeping your bones strong and works in conjunction with a number of other nutrients, most important of which are vitamin D, calcium and magnesium.

The optimal amounts of vitamin K2 are still under investigation, but it seems likely that 180 to 200 micrograms of vitamin K2 should be enough to activate your body's K2-dependent proteins to shuttle the calcium where it needs to be, and remove it from the places where it shouldn't.

As I've discussed on numerous occasions, vitamin D is a critical nutrient for optimal health and is best obtained from sun exposure or a safe tanning bed. However, many are taking oral vitamin D, which can actually be problematic unless you're also getting sufficient amounts of vitamin K2. In fact, this is a really crucial point that has not been emphasized enough in the past: If you opt for oral vitamin D, you need to also consume in your food or take supplemental vitamin K2.

Why?

Because when you take vitamin D, your body creates more vitamin K2-dependent proteins—the proteins that help move the calcium around in your body. But you need vitamin K2 to activate those proteins. If they're not activated, the calcium in your body will not be properly distributed and can lead to weaker bones and hardened arteries.

In short, vitamin K2 ensures the calcium is deposited and removed from the appropriate areas. By taking vitamin D, you're creating an increased demand for K2. And vitamin D and K2 work together to strengthen your bones and improve your heart health.
How Can You Tell if You're Lacking in Vitamin K2?
There's no way to test for vitamin K2 deficiency. But by assessing your diet and lifestyle, you can get an idea of whether or not you may be lacking in this critical nutrient. If you have osteoporosis, heart disease or diabetes, you're likely deficient in vitamin K2 as they are all connected to K2.

If you do not have any of those health conditions, but do NOT regularly eat high amounts of the following foods, then your likelihood of being vitamin K2 deficient is still very high:
Grass-fed organic animal products (i.e. eggs, butter, dairy)
Certain fermented foods such as natto, or vegetables fermented using a starter culture of vitamin K2-producing bacteria. Please note that most fermented vegetables are not really high in vitamin K2 and come in at about 50 mcg per serving. However, if specific starter cultures are used they can have ten times as much, or 500 mcg per serving.
Goose liver pâté
Certain cheeses such as Brie and Gouda (these two are particularly high in K2, containing about 75 mcg per ounce)

Fermented vegetables, which are one of my new passions, primarily for supplying beneficial bacteria back into our gut, can be a great source of vitamin K if you ferment your own using the proper starter culture. They're definitely FAR better than fennel for counteracting bone loss.

We recently had samples of high-quality fermented organic vegetables made with our specific starter culture tested, and were shocked to discover that not only does a typical serving of about two to three ounces contain about 10 trillion beneficial bacteria, but it also contained 500 mcg of vitamin K2. Note that not every strain of bacteria makes K2. For example, most yogurts have almost no vitamin K2. Certain types of cheeses are very high in K2, and others are not. It really depends on the specific bacteria. You can't assume that any fermented food will be high in K2, but some fermented foods are very high in K2, such as natto.
Why Nutritional Interventions are Superior to Drugs
Your bones are made up of minerals in a collagen matrix. The minerals give your bones rigidity and density, but the collagen gives your bones flexibility. Without good flexibility, they become brittle and break easily. So bone strength is MORE than just bone density -- which is why drugs such as biphosphonates have failed so miserably. Drugs like Fosamax build up a lot of minerals and make the bone LOOK very dense on an x-ray called a DEXA scan, which specifically measures bone density, or the degree of mineralization of your bones. But in reality, they are extremely brittle and prone to fracture, which is why there have been so many cases of hip fracture among people taking these damaging drugs.

Biphosphonate drugs are poisons that destroy your osteoclasts, which interferes with your normal bone-remodeling process. You are much better off building your bones using exercise and nutritional therapies, hormones like progesterone and vitamins D and K.
Natural Strategies for Preventing Age-Related Bone Loss
You need a combination of plant-derived minerals for strong bones. Your bones are actually composed of at least a dozen minerals. If you just focus on calcium, you will likely weaken your bones and increase your risk of osteoporosis as Dr. Robert Thompson explains in his book, The Calcium Lie.

It's more likely your body can use calcium correctly if it's plant-derived calcium. Good sources include raw milk from pasture-raised cows (who eat the plants), leafy green vegetables, the pith of citrus fruits, carob, sesame seeds and wheatgrass, to name a few. But you also need sources of silica and magnesium, which some researchers say is actually enzymatically "transmuted" by your body into the kind of calcium your bones can use. This theory was first put forth by French scientist Louis Kevran, a Nobel Prize nominee who spent years studying how silica and calcium are related.

Good sources of silica are cucumbers, bell peppers, tomatoes, and a number of herbs including horsetail, nettles, oat straw, and alfalfa. The absolute best source of magnesium is raw organic cacao. Yes, healthy high quality chocolate is extremely rich in magnesium!

A great source of trace minerals, which are important for many of your body's functions, is Himalayan Crystal Salt, which contains all 84 elements found in your body. In addition, you need to make sure you're eating plenty of vitamin K2, which is found in fermented foods like homemade sauerkraut. Osteocalcin is a protein produced by your osteoblasts (cells responsible for bone formation), and is utilized within the bone as an integral part of the bone-forming process. However, osteocalcin must be "carboxylated" before it can be effective. Vitamin K functions as a cofactor for the enzyme that catalyzes the carboxylation of osteocalcin.

Vitamin K2 has been found to be a far more effective "activator" of osteocalcin than K1 because your liver preferentially uses vitamin K1 to activate clotting factors, while most of your other tissues preferentially use K2. Further, vitamin D, which your body produces in response to sun exposure, is another crucial factor in maintaining bone health as you age.

The bottom line?

One of the best ways to achieve healthy bones is a diet rich in fresh, raw whole foods that maximizes natural minerals so that your body has the raw materials it needs to do what it was designed to do. In addition, you need healthy sun exposure along with regular, weight-bearing exercise.

To sum it up:
Optimize your vitamin D either from natural sunlight exposure, a safe tanning bed or an oral vitamin D3 supplement. Check your blood levels regularly to make sure you're within the optimal range.
Optimize your vitamin K through a combination of dietary sources (leafy green vegetables, fermented foods like homemade sauerkraut and a K2 supplement, if needed. Remember, if you take supplemental vitamin D, you need to also increase your intake of vitamin K2.)

The optimal amounts of vitamin K2 are still under investigation, but it seems likely that 180 to 200 micrograms of vitamin K2 might be enough to activate your body's K2-dependent proteins to shuttle calcium to the proper areas. If you're taking high doses of supplemental vitamin D, Dr. Kate Rheaume-Bleue, a naturopathic physician and author of Vitamin K2 and the Calcium Paradox, suggests taking 100-200 micrograms (mcg) of vitamin K2 for every 1,000 IU's of vitamin D you take. The latest vitamin D dosing recommendations, which call for about 8,000 IU's of vitamin D3 per day if you're an adult, means you'd need in the neighborhood of 800 to 1,000 micrograms (0.8 to 1 milligram/mg) of vitamin K2.
Make sure you do weight-bearing exercise, which has profound benefits to your skeletal systems. My favorite is Peak Fitness but it is also very important to do strength-training exercises to produce the dynamic peizoelectric forces in your bones that will stimulate the osteoblasts to produce new bone.
Consume a wide variety of fresh, local, organic whole foods, including vegetables, nuts, seeds, organic meats and eggs, and raw organic unpasteurized dairy. The more of your diet you consume RAW, the better nourished you will be. Minimize sugar and refined grains.
Bud Karas

Sunday, November 18, 2012

100+ Countries Proves Sunlight Prevents Cancer

100+ Countries Proves Sunlight Prevents Cancer

For the same reason that the conventional energy industry has not harnessed the full potential of solar energy (its free!), sunlight and its indispensable byproduct in our skin: vitamin D, represents a serious threat to the medical establishment, whose questionable and aggressive promotion of vaccination and drug-based strategies in place of inexpensive, safe and effective vitamin D supplementation (or better, carefully meted out recreation and sunlight exposure) for immunity, has many questioning their motives.

Vitamin D, after all, has a vital preventive role to play in hundreds of conditions, due to the fact that 1 in every 10 genes in the human body depends on adequate quantities of this gene-regulatory hormone to function optimally. In other words, the very genetic/epigenetic infrastructure of our health would fall apart without adequate levels.

Even the risk for developing cancer, one of the most feared health conditions of our time -- and the one the medical establishment has had the least success preventing and treating  is intimately connected to your vitamin D status.

Indeed, a groundbreaking new meta-analysis on the sunlight - vitamin D connection, published in the journal Anticancer Research and based on data from over 100 countries, found that "a strong inverse correlations with solar UVB for 15 types of cancer," with weaker, though still significant evidence for the protective role of sunlight in 9 other cancers.
The relevant cancers were
"Bladder, breast, cervical, colon, endometrial, esophageal, gastric, lung, ovarian, pancreatic, rectal, renal, and vulvar cancer; and Hodgkin's and non-Hodgkin's lymphoma. Weaker evidence exists for nine other types of cancer: brain, gallbladder, laryngeal, oral/pharyngeal, prostate, and thyroid cancer; leukemia; melanoma; and multiple myeloma."

Sunlight exposure, after all, is essential for health from the moment we are born. Without it, for instance, infants are prone to developing neonatal jaundice. The very variation in human skin color from African, melanin-saturated dark skin, to the relatively melanin de-pigmented, Caucasian lighter-skin, is a byproduct of the offspring of our last common ancestor from Africa (as determined by mitochondrial DNA) migrating towards sunlight-impoverished higher latitudes, which began approximately 60,000 years ago.

In order to compensate for the lower availability of sunlight, the body rapidly adjusted, essentially requiring the removal of the natural "sunscreen" melanin from the skin, which interferes with vitamin D production. While a life-saving adaptation, the loss of melanin likely has adverse health effects, which include losing the ability to convert sunlight into metabolic energy, increased prevalence of Parkinson's disease (which involves de-melanization of the substantia nigra), and others effects which we will discuss in detail in a future article.

For now, it is important to point out that within the span of only 60,000 years (a nanosecond in biological time), many of the skin "color" differences among the world's human inhabitants reflect how heavily genetically-conserved was the ability of the human body to produce vitamin D.

It should also be pointed out that vitamin D is to sunlight, what ascorbic acid is to the vitamin C activity in food. In other words, sunlight likely provides a greater spectrum of therapeutic activity (when carefully meted out, preferably during solar noon) than supplemental vitamin D3, which is almost exclusively derived from UVB irradiated sheep's lanolin.

For further research, the following link reveals 50 therapeutic effects of sunlight exposure, as culled from research housed on the National Library of Medicine.


Bud Karas